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Bogdan Ovidiu Popescu

Latest posts by Bogdan Ovidiu Popescu (see all)

  • VITAMIN D INTOXICATION IN A PATIENT WITH RELAPSING-REMITTING MULTIPLE SCLEROSIS – CASE REPORT - 19/11/2015
  • BILATERAL PUTAMINAL HEMORRHAGIC NECROSIS FOLLOWING METHANOL POISONING - 15/09/2015
  • CD105/ENDOGLIN EXPRESSION IN A MOUSE MODEL OF ACUTE MUSCLE CONTUSION - 15/09/2015

Articles signed on Romanian Journal of NEUROLOGY:

VITAMIN D INTOXICATION IN A PATIENT WITH RELAPSING-REMITTING MULTIPLE SCLEROSIS – CASE REPORT

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Romanian Journal of Neurology, Volume XIV, No. 3, 2015
ISSN 1843-8148  |  e-ISSN 2069-6094
ISSN-L 1843-8148
DOI: 10.37897/RJN

Indexată BDI  |  IDB Indexed

DOAJ
Ebsco Host - Medline
Scopus
DOI - Crossref

HIGHLIGHTS

Plagiatul – în actualitate

Tema plagiatului este tot mai mult discutată în ultima vreme. Apariția unor programe performante de căutare și identificare a similitudinilor între texte [...]

Committe on Publication Ethics

A forum for responsible and ethical research publishing – Code of Conduct and Best Practice Guidelines for Journal Editors.

VITAMIN D INTOXICATION IN A PATIENT WITH RELAPSING-REMITTING MULTIPLE SCLEROSIS – CASE REPORT

Ioana Cociasu, Irene Davidescu, Ioan Buraga and Bogdan Ovidiu Popescu

ABSTRACT

Lately, vitamin D has been a hot topic among multiple sclerosis specialists. Vitamin D supplementation is being thoroughly researched in order to establish whether or not it is useful in the treatment of multiple sclerosis. We present the case of a patient with multiple sclerosis, who, after searching online, decided to administer vitamin D supplements in high doses; subsequently he was admitted to our for clinic symptoms consistent with vitamin D intoxication.

Keywords: vitamin D, toxicity, multiple sclerosis, relapsing-remitting

Full text | PDF

BILATERAL PUTAMINAL HEMORRHAGIC NECROSIS FOLLOWING METHANOL POISONING

SELECT ISSUE

Romanian Journal of Neurology, Volume XIII, No. 4, 2014
ISSN 1843-8148  |  e-ISSN 2069-6094
ISSN-L 1843-8148
DOI: 10.37897/RJN

Indexată BDI  |  IDB Indexed

DOAJ
Ebsco Host - Medline
Scopus
DOI - Crossref

HIGHLIGHTS

Plagiatul – în actualitate

Tema plagiatului este tot mai mult discutată în ultima vreme. Apariția unor programe performante de căutare și identificare a similitudinilor între texte [...]

Committe on Publication Ethics

A forum for responsible and ethical research publishing – Code of Conduct and Best Practice Guidelines for Journal Editors.

BILATERAL PUTAMINAL HEMORRHAGIC NECROSIS FOLLOWING METHANOL POISONING

Radu Mihailescu, Elena COPACIU, Corina Pop, Amalia Ene and Bogdan Ovidiu Popescu

INTRODUCTION

Although it shares a resemblance with ethanol in both looks and organoleptic properties, methanol is a highly dangerous alcohol. Intoxication with it can lead to severe metabolic acidosis, blindness, neurologic impairment and possiblydeath. Even though generally rare, putaminal necrosis, with or without hemorrhage, is the most common radiologic finding.

Full text | PDF

CD105/ENDOGLIN EXPRESSION IN A MOUSE MODEL OF ACUTE MUSCLE CONTUSION

SELECT ISSUE

Romanian Journal of Neurology, Volume XIII, No. 4, 2014
ISSN 1843-8148  |  e-ISSN 2069-6094
ISSN-L 1843-8148
DOI: 10.37897/RJN

Indexată BDI  |  IDB Indexed

DOAJ
Ebsco Host - Medline
Scopus
DOI - Crossref

HIGHLIGHTS

Plagiatul – în actualitate

Tema plagiatului este tot mai mult discutată în ultima vreme. Apariția unor programe performante de căutare și identificare a similitudinilor între texte [...]

Committe on Publication Ethics

A forum for responsible and ethical research publishing – Code of Conduct and Best Practice Guidelines for Journal Editors.

CD105/ENDOGLIN EXPRESSION IN A MOUSE MODEL OF ACUTE MUSCLE CONTUSION

Antoanela Curici, Elena Codrici, Simona Mihai, Cristiana Pistol Tanase, Bogdan Ovidiu Popescu and Laura Cristina Ceafalan

ABSTRACT

Objectives. Muscle contusion is the most common form of muscle injury and the muscle endogenous regenerative capacity can compensate for non-extensive damage. However, severe traumatic injuries may overcome this capacity. More effective therapeutic strategies are still needed, so the exploration of the molecular context during muscle regeneration might provide new insights.

Materials and methods. We investigated the expression pattern of a reputed angiogenic molecule, CD105/endoglin, by measuring the tissue and serum concentration by multiplex assay in normal and Dmdmdx dystrophic mice by following the distribution of the cellular sources by immunofluorescence in a mouse model of acute muscle contusion.

Results. Maximal tissue concentration in normal animals was obtained 48h post-injury, and then started to decline, with only one other significantly increased value 5 days after injury. In dystrophic mice, tissue levels were globally much higher than in normal animals and started rising 1h post-injury and were maintained elevated all along the regeneration process. In situ immunolabelling highlighted the increased positive population mostly in the inflammatory areas. Double staining separates distinct subsets based on hematopoietic marker CD45 and the endothelial marker CD31 co-expression in endoglin positive cells.

Conclusions. This study offers a timeline of endoglin expression during normal and pathologic muscle regeneration, providing evidence that the major wave corresponds to the inflammatory stage of muscle regeneration, deriving from multiple cellular sources such as endothelial cells, blood cells and also other interstitial cells that become activated during this process.

Keywords: angiogenesis, CD105, endoglin, muscle regeneration

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HEMIBALLISMUS AFTER HEMORRHAGIC STROKE

SELECT ISSUE

Romanian Journal of Neurology, Volume XIV, No. 1, 2015
ISSN 1843-8148  |  e-ISSN 2069-6094
ISSN-L 1843-8148
DOI: 10.37897/RJN

Indexată BDI  |  IDB Indexed

DOAJ
Ebsco Host - Medline
Scopus
DOI - Crossref

HIGHLIGHTS

Plagiatul – în actualitate

Tema plagiatului este tot mai mult discutată în ultima vreme. Apariția unor programe performante de căutare și identificare a similitudinilor între texte [...]

Committe on Publication Ethics

A forum for responsible and ethical research publishing – Code of Conduct and Best Practice Guidelines for Journal Editors.

HEMIBALLISMUS AFTER HEMORRHAGIC STROKE

Vlad Claudiu Stefanescu, Irene Davidescu, Ioan Buraga and Bogdan Ovidiu Popescu

INTRODUCTION

Ischemic or hemorrhagic stroke may be accompanied by movement disorders (1), either hyperkinetic or hypokinetic. Hyperkinetic movement disorders after stroke comprise dystonia (2-4), chorea with or without hemiballismus (5), tremor (6), parkinsonism (7), segmental or focal myoclonus, athetosis, pseudathetosis, and asterixis (8). Hemiballismus is a movement disorder characterized by involuntary, arrythmic, and large amplitude excursion of a limb, usually from a proximal joint, witn an element of rotation (9). Ballismus is explainable with lesions in the subthalamic nuclei, cerebral cortex, corpus striatum, thalamus and brainstem. (10) The frequency of post-stroke abnormal movements is unclear, the prevalence in a swiss registry being 1% with an incidence of 0.08% per year (8). Of them, hemichorea-hemiballismus is the most common, while dystonia is the next most common disorder (11).

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ANTICOAGULATION COMPLICATIONS IN A PATIENT WITH PRIOR CEREBRAL VENOUS THROMBOSIS

SELECT ISSUE

Romanian Journal of Neurology, Volume XIV, No. 2, 2015
ISSN 1843-8148  |  e-ISSN 2069-6094
ISSN-L 1843-8148
DOI: 10.37897/RJN

Indexată BDI  |  IDB Indexed

DOAJ
Ebsco Host - Medline
Scopus
DOI - Crossref

HIGHLIGHTS

Plagiatul – în actualitate

Tema plagiatului este tot mai mult discutată în ultima vreme. Apariția unor programe performante de căutare și identificare a similitudinilor între texte [...]

Committe on Publication Ethics

A forum for responsible and ethical research publishing – Code of Conduct and Best Practice Guidelines for Journal Editors.

ANTICOAGULATION COMPLICATIONS IN A PATIENT WITH PRIOR CEREBRAL VENOUS THROMBOSIS

Ioana Cociasu, Irene Davidescu, Ioan Buraga and Bogdan Ovidiu Popescu

ABSTRACT

Cerebral venous thrombosis is a rare form of stroke treated with anticoagulant compounds both in the acute phase as well as in long term. We present the case of a 56 year old female that suffered two different forms of stroke in 2 years.

Keywords: cerebral venous thrombosis, intracerebral hemorrhage, vitamin K antagonists, hereditary thrombophilia, malignancy

Full text | PDF



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