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Ana-Maria Vladila

Latest posts by Ana-Maria Vladila (see all)

Articles signed on Romanian Journal of NEUROLOGY:

BRAIN MRI FINDINGS IN ACUTE HYPERAMMONEMIC ENCEPHALOPATHY SECONDARY TO ISCHEMIC HEPATITIS: CASE REPORT AND REVIEW OF THE LITERATURE

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Romanian Journal of Neurology, Volume XV, No. 1, 2016
ISSN 1843-8148  |  e-ISSN 2069-6094
ISSN-L 1843-8148
DOI: 10.37897/RJN

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BRAIN MRI FINDINGS IN ACUTE HYPERAMMONEMIC ENCEPHALOPATHY SECONDARY TO ISCHEMIC HEPATITIS: CASE REPORT AND REVIEW OF THE LITERATURE

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ABSTRACT

Acute encephalopathy is frequently seen in Neurology and Internal Medicine Departments, it makes for a wide spectrum of neuropsychiatric abnormalities, but its brain magnetic resonance imaging appearance in the adult population is not well recognised.
We present the case of an acute hyperammonemic encephalopathy in the setting of ischemic hepatitis secondary to global heart failure and its MRI findings with a review of the literature.

Keywords: acute hepatic encephalopathy, hyperammonemia, ischemic hepatitits, insular cortex, FLAIR hypersignal, restriction of diffusion

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PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY ASSOCIATED TO MULTIPLE SCLEROSIS THERAPIES: REVIEW OF THE LITERATURE

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Romanian Journal of Neurology, Volume XIV, No. 4, 2015
ISSN 1843-8148  |  e-ISSN 2069-6094
ISSN-L 1843-8148
DOI: 10.37897/RJN

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PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY ASSOCIATED TO MULTIPLE SCLEROSIS THERAPIES: REVIEW OF THE LITERATURE

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ABSTRACT

Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection associated with the reactivation of the JC virus, causing a severe demyelination within the central nervous system in patients with immunosuppression caused by disease or secondary to use of drugs. Several therapies used in the treatment of MS have reported cases of associated PML, most cases being related to Natalizumab treatment. In this article we review specific MS medication with a reported risk for PML, and also revise PML epidemiology, pathogenesis, treatment and available approaches on therapy in patients at high risk for developing this infection.

Keywords: PML, JC virus, multiple sclerosis, Natalizumab, Fingolimod, dimethyl fumarate, alemtuzamab, PCR, cerebral MRI demyelinating lesion, plasma exchange, Mirtazapine

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MULTIPLE CEREBRAL CAVERNOUS MALFORMATIONS – A CASE REPORT

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Romanian Journal of Neurology, Volume XII, No. 4, 2013
ISSN 1843-8148  |  e-ISSN 2069-6094
ISSN-L 1843-8148
DOI: 10.37897/RJN

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MULTIPLE CEREBRAL CAVERNOUS MALFORMATIONS – A CASE REPORT

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ABSTRACT

Cavernomas are frequent low-flow vascular malformations with a characteristic MRI aspect due to their specific morphology. We present the case of a 64-year old male diagnosed in 2008 with multiple cerebral cavernomas and symptomatic epilepsy, who developed left face, arm and leg paresthesias during the last 6 days. The MRI examination performed in our clinic showed increased number of infracentimetic lesions with no signs of hemorrhage or growth of the previous documented ones. Considering MRI findings and the patient being seizure free for the last three years there is no current indication for invasive treatment. The presence of multiple lesions along with their aspect on T2* MRI sequences suggest a hereditary form in absence of familial history of cerebral cavernous malformations.

Keywords: multiple cerebral cavernomas, symptomatic epilepsy, MRI T2*

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CHRONIC SUBDURAL HEMATOMA: A CASE REPORT AND REVIEW OF THE LITERATURE

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Romanian Journal of Neurology, Volume XIII, No. 1, 2014
ISSN 1843-8148  |  e-ISSN 2069-6094
ISSN-L 1843-8148
DOI: 10.37897/RJN

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CHRONIC SUBDURAL HEMATOMA: A CASE REPORT AND REVIEW OF THE LITERATURE

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ABSTRACT

Chronic subdural hematoma is a common type of intracranial hemorrhage with higher incidence and unpredictable evolution among elderly people. We present the case of a 73 years old male patient, diagnosed in October 2013 with subacute bilateral subdural hematomas who was admitted in our clinic for worsening of motor function in his left limbs. The cerebral CT performed revealed a right massive chronic subdural hematoma which met the criteria for neurosurgical approach requiring a large craniotomy for complete removal. In this article we review the risk factors associated with an unpredictable evolution and postoperative subdural hematoma recurrence in the elderly.

Keywords: chronic subdural hematoma, elderly, epilepsy, atrial fibrillation, antiplatelet/ anticoagulant medication, large craniotomy, bleeding, subdural hematoma recurrence

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