Marius Militaru, Anda Militaru, Stanca Ples, Gratian Miclaus, Mihaela Simu and Daniel LIGHEZAN

ABSTRACT

Nearly 25%-30% of ischemic strokes are due to atherosclerosis of the carotid bifurcation. Cerebrovascular reactivity (CVR) is an indicator for testing hemodynamic status of cerebral circulation. The purpose of the presentation was to determine the effects of CEA (endarterectomy) on cerebral hemodynamics with cerebral hemodynamic change tracking, by measuring the average flow velocities (MFV) in the ipsilateral and contralateral middle cerebral artery (MCA) severe carotid stenosis and pulsatility index (PI) by the help of the Transcranian Doppler (TCD) and the study of CVR (cerebrovascular reactivity) by performing BHT (Breath-holding test) both before and at 7 days and at 2 and 4 months post intervention, as well as cerebral hemodynamic parameters determining through Cerebral Perfusion CT and correlation with risk factors and prior stroke event. Using ultrasound methods ECD (Extracranial Doppler) and TCD (Transcranial Doppler) and imaging (Perfusion Cerebral CT, angioCT cervical region, angiocoronarography) allowed: increased detection of patients at risk of stroke and myocardial infarction, stroke diagnosis of ischemic sites, the calculation of hemodynamic parameters of cerebral circulation at patients with coronary stenosis and carotid stenosis, occlusion with stroke up, TIAs or stroke risk and heart attack.

Keywords: carotid stenosis > 70%; transcranian Doppler – breath-holding test, cerebrovascular reactivity, CT perfusion, carotid endarterectomy

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